What does it mean when cervical mucus tests positive for anti-sperm antibodies?

There are many causes of infertility. Cervical mucus anti-sperm antibodies are a very common type of immune infertility. Suffering from this disease usually leads to infertility in women. For women who want to have children, it is a huge blow. However, after the cervical mucus anti-sperm antibodies become positive, active treatment is required. You must take it seriously and don't be careless. However, many people don't know much about this disease. The following is a detailed introduction to cervical mucus anti-sperm antibodies.

What does it mean when cervical mucus is positive for anti-sperm antibodies?

For women, a positive anti-sperm antibody means that after the male sperm enters the female uterus, it will be mistaken by the female immune cells as a foreign body invading the human body, causing rejection, resulting in the male sperm being swallowed up.

The reason why women test positive for anti-sperm antibodies is that AsAb has the functions of phagocytizing, killing, braking and agglutinating sperm, which often causes fatal setbacks in the combination of sperm and egg. In addition, women with positive antisperm antibodies often suffer from reproductive system inflammation such as vaginitis, endometritis, and salpingitis before the onset of the disease.

A positive anti-sperm antibody is actually an obstacle that can prevent the sperm and egg from combining, causing complement-mediated dissolution of the fertilized egg, damaging embryo implantation and early embryonic development, leading to embryonic maldevelopment, and causing early miscarriage.

Positive anti-sperm antibodies can also interfere with sperm like electromagnetic waves, affecting sperm movement. If sperm cannot move normally, it cannot effectively combine with the egg, resulting in inability to conceive.

What to do if anti-sperm antibodies are positive

1. Immunosuppressive therapy

Immunosuppressive therapy mainly uses various types of adrenal cortical hormones to treat the symptoms of immune infertility. According to the female's physiological cycle, the time of ovulation is estimated, and the trial begins two weeks before the ovulation cycle. It can have a local hydrogenation effect on the female's cervical mucus and vagina, greatly improving the female's pregnancy rate.

2. Intrauterine artificial insemination

Intrauterine artificial insemination is mainly aimed at anti-sperm antibodies caused by the condition of cervical mucus. The best way to deal with cervical mucus is to use artificial insemination. The husband's semen is taken out, and the sperm of good quality is taken out. After separation, it is placed in the female's uterine cavity.

Positive anti-sperm antibodies are a serious obstacle to women's pregnancy and are a type of immune infertility. For this type of infertility, hospitals generally use immunosuppressive therapy and intrauterine artificial insemination to help more couples realize their desire to have children.