When should I pay attention to when to transplant frozen blastocysts for the second time?

If it is the second time to transplant frozen blastocysts, you must maintain good physical condition at ordinary times, try not to stay up late, and do not overwork. You must get enough sleep, keep a good mood, strengthen nutrition appropriately, and enhance your physical fitness. This will increase the success rate. However, don't worry too much during the transplant, just deal with it with a normal mind, and always maintain a good attitude.

The process of freezing embryos:

1. Preparation of the endometrium.

Preparation of the endometrium, development of the embryo, and synchronization of the endometrium are important conditions for the success of pregnancy after thawed embryo transfer. The main methods of endometrial preparation are: natural cycle method and hormone replacement method.

(1) Natural cycle method : For women with regular menstruation and normal ovulation, transplantation should be performed during the ovulation period. Ultrasound monitoring and a series of tests such as blood endocrine tests should be performed before transplantation.

(2) Hormone replacement method : Women with irregular menstrual cycles and ovulation disorders must use drugs to promote the growth of the endometrium. Only when the endometrium reaches a certain level of morphological development can it be resuscitated and the embryo transplanted.

2. Thaw the embryos . Thaw the frozen embryos. If any embryos are damaged during the thawing process, they will be discarded. When selecting embryos, the integrity of the frozen-thawed embryo's blastomeres and the ability of the cells to further divide are mainly considered. When transplanting, try to choose embryos with intact blastomeres and those that continue to divide.

3. Transplant the embryo . On the day of transplantation, 3 embryos are thawed first. If the number of surviving embryos is less than 3, they will continue to be thawed until 3 surviving embryos are available for transplantation.

4. Inject progesterone . Although frozen embryo transfer can be performed at the right time, because the embryo is not fertilized in the female body, the female body is not completely synchronized with the embryo and does not produce enough progesterone for the embryo to implant and develop, so progesterone needs to be artificially ingested. The injection dose can be less than that of fresh embryo transfer. Most doctors will use 40 mg/day of progesterone injection, but doctors will also adjust the dose according to the individual patient's situation.

5. Confirm pregnancy . Generally, if you do not have your period two weeks after the transplant, you can go to the hospital to test whether you are pregnant. After a successful pregnancy, you need to continue taking corpus luteum to protect the fetus and perform an ultrasound test after two weeks.