Gonorrhea leucorrhea picture

Gonococcal vaginitis refers to vaginitis caused by gonococci. Pathogen - caused by gonococci, which can be infected through unclean or disordered sexual life. There are also very few cases of indirect infection through wearing swimwear infected with Chlamydia or passing through bathtubs and toilets contaminated with Chlamydia. Its symptoms include lower abdominal pain, increased female secretions, leucorrhea with a texture of tofu residue, redness, swelling and pain in the vaginal opening, etc. If not treated immediately, it may turn into chronic gynecological inflammation. 10% to 20% of women may experience infertility or ectopic pregnancy.

Pathogens of gonococcal vaginitis

The pathogen that causes gonorrhea is Neisseria gonorrhoeae, also known as Chlamydia. This type of pathogen has the ability to self-adapt and can acquire drug resistance through genetic mutation, or at least make the drugs less effective, and it is developing this immunity to more and more types of antibiotics. First penicillin was ineffective against it, then tetracycline, ciprofloxacin, and now cephalexin.

Gonorrheal vaginitis

In 1879, Neisser isolated gonococci from the specimens of 35 patients with acute urethritis, vaginitis and subacute conjunctivitis in newborns. In 1885, Bumm successfully cultured Chlamydia in the coagulated blood cell culture medium of humans, cattle or sheep, and the same symptoms could be induced by injecting the bacteria into the urethra of normal people. At this point, it was established that Chlamydia was the causative agent of gonorrhea.

Gonorrheal vaginitis shape

The shape is similar to that of the colored chlamydia, which is oval or bean-shaped, with a length of 0.6 to 0.8 μm and a width of about 0.5 μm. They are often arranged in pairs, with adjacent surfaces flat or slightly concave, like two soybeans paired together. There are no microvilli and no spores are produced. In subacutely infected organisms, their shape is more typical and they are mostly located in the cytoplasm of the cells. The onset of the disease is outside the body cells. Gram stain for Chlamydia was negative. When colored with methylene blue, the bacteria appear dark blue. When colored with Pappehheim Saathof, the bacteria appear bright red and the surrounding tissues appear light blue, which is very clear.

Gonorrheal vaginitis structure

The key to the pathogenesis of Chlamydia is closely related to the structure of the bacterial body. The outer structure of Chlamydia is the outer membrane, the main components of which are membrane proteins, lipopolysaccharides and fimbriae. Membrane proteins allow Chlamydia to adhere to the human mucosa, enter cells through phagocytosis, multiply in large numbers inside the cells, causing cell lysis, and spread the Chlamydia out to the lower layer of the mucosa to cause infection. The pili easily adhere to the surface of the uterine body and oral squamous epithelial cells and are pathogenic and infectious.

Gonorrheal vaginitis resistance

Chlamydia is relatively delicate and is most afraid of dryness. It is suitable for growth in a humid environment with a temperature of 35-36°C and 2.5%-5.0% carbon dioxide. The suitable pH for its growth is 7.0-7.5. Chlamydia has very poor resistance to external physical and chemical factors. It will die within 1 to 2 hours in a completely dry environment. However, if it adheres to clothes and quilts, it can survive for 18 to 24 hours, and can survive for several days in thick liquid or moist objects. It can only survive for 5 minutes at 50℃. Chlamydia is too weak to resist common mucosal pesticides. The Chinese Academy of Microbiology used the commonly used Jiaoyan Clean Vaginal Wash for testing. The chlamydia was completely eliminated within 1 minute under the action of Jiaoyan Clean Vaginal Wash. Chlamydia is also very sensitive to soluble silver salts. A 1:4000 silver nitrate solution can kill it within 7 minutes, and the chlamydia in the concentrated solution can die within 2 minutes. 1% formic acid (carbolic acid) aqueous solution can eliminate it within 3 minutes. Except for drug-resistant strains, Chlamydia is relatively sensitive to antibiotics, but the minimum antibacterial concentration of antibiotics gradually increases.