Effects of growth hormone on ovarian follicles

Many newly married couples have a special passion for children and hope to have a child as soon as possible after marriage. However, this matter must not be rushed, and preparations for pregnancy must be made in a scientific and standardized manner. Many people do not know much about the effects of growth hormone on eggs. Below I will give you a detailed description of the effects of growth hormone on eggs. Those who do not understand must come and learn about it.

Effects of Children's Growth Hormone on Eggs

1. The effect of growth hormone on egg cell and uterine development is exerted through insulin-like growth factor-1 (IGF-1). Growth hormone stimulates IGF-1 in blood cells and eggs, and promotes the liver to convert IGF-1. IGF-1 protein kinase is present in oocytes, granulosa cells and theca cells.

2. Clinical experiments have shown that growth hormone can improve the cytoplasm and cytoplasm of oocytes, promote the production of steroid hormones in granulosa cells, and improve the nude oocytes in IVM.

3. The membrane protein in the egg cell serves as the energy processing factory of the body cell and is closely related to the growth potential of the body cell. Children's growth hormone improves the mitochondrial function in the egg cell, thereby improving the quality of the egg cell and enhancing its growth potential.

What is the actual effect of using children's growth hormone for patients with low uterine and ovarian response?

Although the standards for uterine and ovarian hyporesponse are different in different references, studies have found that the use of pediatric growth hormone is effective for patients with hyporesponse. The largest clinical trial on growth hormone so far is the "LIGHT" experiment conducted by Canadian biologists. This is a randomized, double-blind, placebo-controlled trial. The experimental group was given a total of 12 IU growth hormone from the beginning of ovulation induction, and the control group was given a placebo. The results confirmed that growth hormone can improve the responsiveness of the uterus and ovaries to ovulation induction, but there is no improvement in the success rate. Roger J. Hart conducted a meta-analysis of all studies on the use of growth hormone in patients with ovarian hyporesponsiveness in recent years and found that although the dosage and duration of growth hormone used varied among different experiments, growth hormone was still beneficial for patients with hyporesponsiveness in terms of the number of eggs retrieved and the number of sperm-egg combinations. Although clinical pregnancy rates increased, the success rate did not improve after the use of pediatric growth hormone.

The above is some detailed explanation about "the effect of children's growth hormone on eggs". I hope that mothers who are preparing for pregnancy will have a good heart rate, not be too anxious, have a good diet and good sleep quality to support a good body. The health of the baby is closely related to the preparations for pregnancy. I hope that parents who have read this article will pay attention to this.