What should I do if the inflammation below is very painful?

In fact, women are more prone to diseases in normal times because the structure of women's gynecological organs is more complicated than that of men. Women's bodies include not only ovaries, which often have more functions than lungs, and uterus, but also pelvic tissues, which can lead to vaginal inflammation, itching, pain, and extreme discomfort.

Pathological etiology

In normal women of childbearing age, under the action of endocrine hormones, the vaginal epithelial cells proliferate and their surface cells are rich in glycogen, which is very conducive to the growth of facultative anaerobic lactobacilli. This bacterium accounts for more than 90% of the vagina. The presence of a large number of this lactobacilli inhibits the growth of other pathogenic bacteria and forms a normal ecological balance in the vagina.

When the body's estrogen level drops, it causes vaginal epithelial atrophy and a decrease in cell glycogen, which is not conducive to the growth of lactobacilli. Excessive use of antibiotics or excessive flushing of the vagina with alkaline fluids inhibits the growth of lactobacilli. Promiscuous sex and frequent sexual intercourse (because the pH of semen is 7.2-7.8) lead to the proliferation of pathogenic anaerobic bacteria and Gardnerella, causing an imbalance in the ecological balance of vaginal microorganisms, a decrease in facultative aerobic lactobacilli, and ultimately leading to bacterial vaginosis.

The decarboxylase produced by anaerobic bacteria can stimulate Gardnerella to produce certain amino acids, resulting in volatile amines, which release an unpleasant fishy smell. Amines increase the pH value and inhibit the reproduction of lactobacilli. The vaginal epidermal cells that are attached to bacteria fall off, increasing vaginal secretions, thus leading to this disease. Due to the disorder of flora, vaginal inflammation is not obvious, and the white blood cells in the secretions are reduced. Therefore, bacterial vaginosis is more appropriately called vaginitis than vaginitis.

Disease diagnosis

Differentiate from Trichomonas vaginitis, Candida vaginitis, senile vaginitis, etc.

Inspection method

Laboratory examination is very necessary for the diagnosis of this disease. The disease cannot be diagnosed if there is an increase in leucorrhea without laboratory examination. Laboratory examination includes smear, amine test, culture method, biochemical method, fluorescent antibody method, etc. Smear method and amine test are simple and easy to operate laboratory methods, which are very helpful for diagnosis. If conditions permit, culture or fluorescent antibody test can be performed.

(1) Smear microscopy: Clue cells can be found by taking a smear of secretions. Clue cells are epithelial cells with a large number of Gardnerella attached to their surface. The characteristic of clue cells is that the surface of the epithelial cells is rough or has fine particles, as if sprinkled with a layer of flour. The bacteria are Gram-negative coccobacilli.