Who needs to check six hormones?

The six-item hormone test is a relatively common examination method. When women have irregular menstruation or are unable to conceive, they can use this method to check. It is also a relatively important examination method. It is a multi-examination, after such examination, the cause of the disease can be determined, or combined with other examinations, and then good treatment can be carried out. Let us learn about it.

By measuring the levels of sex hormones, we can understand the female endocrine function and diagnose diseases related to endocrine disorders. The six commonly used sex hormones, namely follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), progesterone (P), testosterone (T), and prolactin (PRL), basically meet the needs of clinicians for screening of endocrine disorders and general understanding of physiological functions.

There are many tests in the six-item sex hormone test, which can check many diseases. Therefore, the six-item sex hormone test is a common test item. The six-item sex hormone test is a commonly used test method for patients with endocrine disorders. Through the six-item sex hormone test, it can be determined whether there is an endocrine disease, and then the treatment method can be determined according to the test results.

1. Ovarian failure: Basic FSH>40IU/L, LH increased or>40IU/L, it is high gonadotropin (Gn) amenorrhea, that is, ovarian failure. If it occurs before the age of 40, it is called premature ovarian failure (POF).

2. Basal FSH and LH are both less than 5IU/L, which is low Gn amenorrhea, indicating hypothalamic or pituitary dysfunction. The distinction between the two requires the use of gonadotropin-releasing hormone (GnRH) test.

3. Poor ovarian reserve (DOR): Basal FSH/LH>2-3.6 indicates DOR (FSH can be within the normal range), which is an early manifestation of ovarian dysfunction. It often indicates that the patient responds poorly to superovulation (COH). The COH regimen and Gn dose should be adjusted in time to improve ovarian responsiveness and obtain an ideal pregnancy rate. Because the increase in FSH/LH only reflects DOR rather than a decrease in fertility, an ideal pregnancy rate can still be achieved once the ovulation period is reached.

5. Polycystic ovary syndrome (PCOS): Basal LH/FSH>2-3, which can be used as the main indicator for diagnosing PCOS (basal LH level>10IU/L is elevated, or LH maintains a normal level, while the basal FSH is relatively low, resulting in an increased LH to FSH ratio).

6. If the basal FSH level is >20IU/L in two examinations, it can be considered as the latent stage of premature ovarian failure, indicating that amenorrhea may occur after one year.