How to treat corpus luteum deficiency

Insufficient corpus luteum often leads to infertility and poses a great threat to women's health. At this time, good treatment should be carried out in time. The treatment method is to supplement progesterone and also to carry out chorionic gonadotropin treatment. In daily life, we should also emphasize rationality, maintain an optimistic attitude, and pay special attention to diet regulation, which will help the treatment results. Different treatments should be given according to different symptoms.

(1) Progesterone supplementation therapy: This method is the most widely used. Regardless of the cause, it can be used for patients who are found to have low progesterone levels in the mid-luteal phase, poor secretion in endometrial uterine tissue examination, or who are confirmed to have luteal insufficiency through clinical observation. The specific method is: ① Insert 25 mg of progesterone vaginal suppository deep into the vagina or rectum, once in the morning and evening, by the patient for self-use, starting 2 days after the basal body temperature rises (the 16th or 17th day of the menstrual cycle) and ending when menstruation comes.

② Progesterone oil, 10 mg intramuscularly injected daily, or 20 mg intramuscularly injected every other day, used from the second day after the basal body temperature rises. ③Synthetic progesterone: 2 mg of progesterone acetate, 3 times a day, or 5 mg every night. Start taking the medicine 2 days after the basal body temperature rises. Hydroxyprogesterone: Intramuscular injection twice a week, 125 mg each time, starting on the second day after the basal body temperature rises.

(2) Human chorionic gonadotropin (hCG): It can induce ovulation before ovulation and stimulate corpus luteum development after ovulation, support corpus luteum function, increase progesterone synthesis, and prolong corpus luteum life. The usage is to inject hcg 2000-3000U intramuscularly every other day starting from 3-4 days after ovulation, for a total of 3-4 times; or to inject 1000U intramuscularly every day starting from 3 days after ovulation, for 7-8 consecutive days.

(3) Clomiphene: The use of clomiphene to induce ovulation has been found to have poor luteal function in some patients. However, there are reports that for patients with natural ovulation, especially when progesterone supplementation therapy is ineffective, taking clomiphene 50 mg daily in the early follicular phase, that is, from the third day of the menstrual cycle, for 5 consecutive days can increase the pregnancy rate.

(4) Bromocriptine: Infertile patients with luteal dysfunction accompanied by elevated serum prolactin can be treated with bromocriptine: 1 to 2 times a day, 2.5 mg each time.