What is the cause of infertility due to immature ovarian follicles?

The function of the follicle is to release the egg. If there is an abnormality in the follicle, it means that the egg cannot combine normally with the sperm to form a fertilized egg. Clinically, immature follicle development is one of the reasons why women cannot become pregnant, which brings great psychological trauma to women, after all, they lose the opportunity to become mothers. In this case, we need to find the cause in order to better treat it. What is the cause of infertility due to immature ovarian follicles?

There are many reasons for the immature development of follicles. From the results of transvaginal ultrasound monitoring of many women, the following points can be summarized:

1. Normal ovulation type: The largest follicle appears on the 10th to 16th day of menstruation, ovulation occurs on the 12th to 18th day, and the maximum diameter of the follicle is 18 to 30 mm. BBT had 13 cycles that were biphasic, 2 cycles that were atypical biphasic, and 1 cycle that was monophasic. Ellipsoidal bodies were found in cervical mucus during the luteal phase in 10 cycles, and fern-like crystals coexisted with ellipsoid bodies in 6 cycles.

2. Delayed ovulation type: B-ultrasound monitoring shows that the maximum average diameter of the follicles appears on the 26th to 37th day of menstruation, with a maximum average diameter of 16 to 36 mm, and ovulation occurs on the 21st to 40th day of menstruation. The menstrual cycle lasts 66 to 73 days. The development of this type of follicles is irregular. Some develop to maturity, remain unchanged for several days, and then suddenly ovulate; others develop to a certain extent, remain unchanged for several days, then grow rapidly and ovulate quickly. BBT showed biphasic in 51 cycles, atypical biphasic in 1 cycle, and monophasic in 1 cycle. Ellipsoidal bodies were found in cervical mucus during the luteal phase of 48 cycles, and fern-like crystals and ellipsoidal bodies coexisted during the luteal phase of 5 cycles.

3. No follicular development type: No cystic echoes with a diameter ≥5mm are seen, and they disappear on their own. BBT was monophasic in all cases, and cervical mucus was persistently fern-like.

4. No superior follicle formation type: until the onset of menstruation, the maximum diameter of the follicle in no cycle is ≥15mm, and the follicle shape is irregular and the tension is low. BBT was monophasic in 25 cycles and atypical biphasic in 9 cycles. Cervical mucus was persistently fern-like in 29 cycles and small ellipsoids were seen in 5 cycles.

5. Luteinized unruptured follicle type: After 11 cycles, the upper follicle continues to grow larger after formation, the capsule gradually becomes thicker, the boundary gradually becomes blurred, the vesicle tension decreases, and the cyst gradually becomes uneven and low-echo. The maximum diameter of the vesicle can reach 67 mm, and it gradually decreases and disappears after menstruation. The BBT was biphasic in all cases, and ellipsoids were found in the cervical mucus.

It is not very difficult to treat immature follicular development. The most important thing is early diagnosis and early treatment, using scientific treatment methods. Normally, there are no obvious symptoms of immature follicle development, so women themselves cannot feel it. If you suddenly find that your menstruation becomes very irregular and your body temperature fluctuates greatly, it is best to go to the hospital for a physical examination.