What is the normal level of estradiol during pregnancy?

Estradiol is an estrogen therapy that is absorbed through the skin. It can supplement the deficiency of 17-β estradiol secreted by female ovaries, while avoiding the side effects caused by oral administration (breast pain, weight gain, high blood pressure, gallstones and abnormal liver function, etc.). Estradiol is commonly used to treat female hypogonadism, bilateral oophorectomy, atrophic vaginitis, vulvar dryness, menopausal syndrome such as hot flashes, sweating, and mental and neurological symptoms. What is the normal level of estradiol during pregnancy? Find out through the following article.

Early pregnancy: 0-300 ng/L

Second trimester: 1000-8000 ng/L

Late pregnancy: 5000--27000ng/L

[Clinical significance] Since the effect of estriol on non-pregnant women is much weaker than that of estradiol, the determination of serum estriol is generally only used in pregnant women.

1. The serum estriol level increases continuously with the progress of pregnancy until it drops slightly before delivery. When serum estriol decreases and estradiol increases at the same time, it indicates poor placental function and often indicates premature birth.

2. Continuous monitoring of serum estriol in pregnant women can be used for monitoring high-risk pregnancies. If the estriol level continues to decrease, it indicates severe placental dysfunction, and intrauterine fetal growth retardation, preeclampsia, fetal congenital malformations, hydatidiform mole, intrauterine stillbirth, etc. often occur.

3. Elevated serum estriol levels in pregnant women can be seen in multiple pregnancies, pregnancy complicated by diabetes, and congenital hyperadrenocortical syndrome of the fetus.

What is the normal level of estradiol during pregnancy? I believe you have a certain understanding through the above article. Avoiding tobacco and alcohol during pregnancy does not only mean not smoking or drinking, but also not staying in a smoky environment for a long time. Passive smoking can also cause harm to the child. If you feel any abnormality or discomfort in your body, it is best to go to the obstetrics and gynecology department for treatment. Never take medicine at will. Any medications you have been taking before must also be continued with the doctor's consent.