Effect of endometrial thickness of 1.2 cm

What is related to the endometrial thickness of 1.2cm? What effect would such thickness have? Will it be easy to get hurt? Will there be any other problems and impacts? What should we understand and know? Is this thickness normal? What is the normal thickness? Let’s take a look at the role of endometrial thickness.

1. Overview

The normal thickness of the endometrium is different at different stages of the menstrual cycle. If the endometrium is thick, menstruation will be painful and the fertilized egg will not be easy to implant. Generally speaking, the normal thickness of the endometrium is 0.2-1.0 cm. During menstruation, the functional layer of the endometrium is shed and the basal layer is preserved. The proliferative phase is from the 6th to the 14th day of menstruation, and the normal thickness of the endometrium is about 1-3mm. The secretory phase is from day 15 to day 28 of the menstrual cycle, and the thickness of the endometrium is about 5 to 7 mm.

Second change

The normal cyclical changes in endometrial thickness can be divided into three phases:

1. Proliferative phase: The 5th to 14th day of the menstrual cycle, which is equivalent to the stage of follicle development and maturation. Under the action of estrogen during the follicular phase, endometrial glands and interstitial cells proliferate. The proliferative stage is divided into three stages: early, middle and late. 1) Early proliferative phase: Day 5-7 of the menstrual cycle. The proliferation and repair of the endometrium begins during the menstrual period. During this period, the endometrium is relatively thin, only 1 to 2 mm. Glandular epithelial cells are cuboidal or low columnar. The stroma is dense and the cells are star-shaped. The arterioles in the interstitium are straight and thin-walled. 2) Mid-proliferative phase: 8th to 10th day of the menstrual cycle. This stage is characterized by obvious interstitial edema; the number of glands increases, they grow, and they become curved; the glandular epithelial cells proliferate actively, the cells are columnar, and they show signs of division. 3) Late proliferative phase: 11th to 14th day of the menstrual cycle. During this period, the normal thickness of the endometrium increases to 3-5mm, and the surface is uneven and slightly wavy. The epithelial cells are tall columnar, the glandular epithelium continues to grow, the number of nuclear divisions increases, the gland becomes longer, and forms a curved shape. The interstitial cells are star-shaped and combined into a network; the tissue edema is obvious, the arterioles are slightly curved, and the lumen is enlarged.

2. Secretory phase: After the corpus luteum is formed, the endometrium shows a secretory reaction under the action of progesterone. The secretory phase is also divided into three stages: early, middle and late. 1) Early secretory phase: Day 15-19 of the menstrual cycle. During this stage, the endometrial glands are longer and more curved. Small vesicles containing glycogen begin to appear under the nuclei of glandular epithelial cells, called subnuclear vacuoles, which are histological features of the early stage of secretion. 2) Mid-secretory phase: Day 20-23 of the menstrual cycle. The inner membrane is thicker and more serrated than before. The apical cell membrane of the secretory epithelial cells in the gland ruptures, and the glycogen in the cells is discharged into the glandular cavity, which is called apocrine secretion. During this period, the interstitial tissue is highly edematous and loose, and the spiral arterioles proliferate and curl. 3) Late secretory phase: Day 24 to 28 of the menstrual cycle. This period is the pre-menstrual period.

3. Menstrual period: Day 1 to 4 of the menstrual cycle. At this time, the levels of estrogen and progesterone decrease, activating the synthesis of prostaglandins in the endometrium. Prostaglandins can stimulate the contraction of the uterine muscle layer and cause continuous spasm of the spiral arterioles in the functional layer of the endometrium, resulting in a decrease in endometrial blood flow. The area of ​​damaged, ischemic, and necrotic tissue gradually expands. Tissue degeneration and necrosis, increased permeability of the blood vessel wall, and rupture of the blood vessels lead to the formation of hematoma at the bottom of the intima, which promotes tissue necrosis and exfoliation. The degenerated and necrotic endometrium mixes with blood and is discharged to form menstrual blood. The normal thickness of the endometrium can reach 8-10mm.

I believe that after reading the above content, you will know the relevant content about the thickness of the endometrium, its principles, and related content about preventive measures. Therefore, for the sake of women's health, you must take a good look at the preventive measures and take action to eliminate the possibility of endometrial injury from the root of the disease. The uterus is the key protection object for women. Everyone must learn to take care of the more sensitive and fragile parts of their body, keep them away from harm, keep themselves away from troubles, strengthen their own cleanliness, and protect the health of the uterus.