What are the causes of left ovarian mucinous cystadenoma?

Ovarian mucinous cystadenoma is a relatively common disease. For patients with left-sided ovarian mucinous cystadenoma, it is very necessary to understand the cause of the left-sided ovarian mucinous cystadenoma. So what are the causes of left-sided ovarian mucinous cystadenoma? Next, this article will introduce you to the relevant knowledge about left-sided ovarian mucinous cystadenoma. Friends who want to know the causes of left-sided ovarian mucinous cystadenoma can take a look!

Ovarian mucinous cystadenomas account for 20% of benign ovarian tumors. 95% of the tumors are unilateral, with a grayish-white surface, large or huge size, and often multi-chambered cross-sections with cystic cavities of varying sizes. The cyst septa are composed of connective tissue, the cystic fluid is gelatinous and contains mucin or glycoprotein. The tumor surface is smooth and rarely has papillary growth. The cyst cavity is covered with a single layer of tall columnar epithelium that can produce mucus. The malignant transformation rate is 5-10%.

2%-5% of patients with ovarian mucinous cystadenoma have peritoneal myxoma, which is usually secondary to cyst rupture. Tumor cells implant in the peritoneum and form tumor nodules, producing a large amount of mucus, but generally no organ parenchymal infiltration occurs. It is not easy to completely remove the tumor during surgery and it is very easy to relapse after surgery. The 5-year survival rate is only 45%. The tumor epithelium is highly differentiated and is insensitive to radiotherapy or chemotherapy.

What are the causes of left ovarian mucinous cystadenoma? It is currently believed that ovarian mucinous cystadenoma originates from the metaplasia of ovarian surface epithelium or coelomic epithelium inclusion cysts. There is much evidence that mucinous tumors may contain other Müllerian-type epithelia such as fallopian tube-type and endometrioid epithelia. Transition zones between coelomic epithelial inclusion cysts and mucous epithelium can also be seen. However, goblet cells, argyrophilic cells, and Paneth cells can be seen in some mucinous tumors; and mucinous glands and cysts are often components of teratomas. About 5% of mucinous tumors are accompanied by benign cystic teratomas. Therefore, some people believe that mucinous tumors may originate from germ cells and are very similar to monoembryonic tumors. However, organs of mesoderm origin such as the kidney and cervix can also show intestinal metaplasia and appear the above-mentioned cells. Similar metaplasia of the ovarian surface epithelium could explain the origin of intestinal-type mucinous tumors. Occasionally, endocervical and intestinal epithelium may coexist in the same tumor or even in the same gland.

Some scholars believe that the disease seems to have a genetic tendency. For example, among genetic diseases, Peut-JeGHres syndrome is characterized by skin and mucous membrane pigmentation and gastrointestinal polyps. About 14% of patients have ovarian tumors, either granulosa cell tumors or cystadenoma.

The above is an introduction to the causes of left ovarian mucinous cystadenoma. I believe that after reading the above introduction, you will have a clearer understanding of the causes of left ovarian mucinous cystadenoma. I hope that through the above introduction, everyone will have a better understanding of the disease of ovarian mucinous cystadenoma.