Causes of vulvovaginitis

I believe everyone is familiar with the disease of vulvovaginitis in life. This is a very common disease with a very high incidence rate. A little carelessness may lead to the occurrence of this disease. However, there are many reasons for the occurrence of this disease. It is not only because of not paying attention to personal hygiene in life. Let us understand the causes of vulvovaginitis together.

Specific reasons:

Vulvovaginitis is an inflammation and irritation of the vagina and vulva, most often caused by pathogenic microorganisms. The infection usually begins in the vagina. The most common symptoms are vulvar itching and/or burning, increased vaginal discharge and an unusual odor. Not all vaginitis conditions (vaginitis) necessarily cause vulvar irritation. Patients with chlamydial infection of the cervix may also complain of increased vaginal discharge. Atrophic vaginitis is a noninfectious cause of vaginal irritation in postmenopausal women secondary to estrogen deficiency.

1. Medical history, symptoms and signs.

2. Microbiological examinations include bacteria, viruses, protozoa, spirochetes, CT, UU smear staining, bacterial and viral culture, serological and immunological examinations. It is known that bacterial vaginosis (BV) secretions have characteristic clue cells, pH>4.5, potassium hydroxide test (+) and proline aminopeptidase (+). It is worth pointing out that modern advanced cell and molecular biology detection methods such as polymerase chain reaction (PCR), protein blot, enzyme-linked immunosorbent assay (ELISA) and monoclonal antibody detection technology have been widely used in clinical practice, providing an effective means for accurate and timely diagnosis of gynecological infectious diseases.

3. Histopathological examination: Certain specific infection lesions should be examined to determine their etiology and pathological changes. Such as tuberculosis, amoeba, syphilis, genital warts, etc. The pathological characteristics of condyloma acuminatum are papillary hyperplasia of the squamous epithelium, hypertrophy of the prickle cell layer and cell atypia, that is, they show typical koilocyte characteristics. The nuclei of prickle cells were stained darkly and irregularly, with an oval blank area around the nucleus, which was stained with PAS (-). Under electron microscopy, glycogen granules and organelles were missing in the hollowed-out area, with only a small number of ribosomes. Nuclear chromatin is condensed and virus particles can be seen in the nucleus. Immunohistochemistry and in situ PCR techniques can be used to diagnose the intracellular localization of HPV.

The above article introduces a detailed explanation of the causes of vulvovaginitis. I believe everyone has a certain understanding of this. If you are exposed to this disease in your life, you must pay special attention to your hygiene and wear loose and comfortable underwear.