Know more about medicine | Is it necessary to use antiplatelet drugs in combination to prevent stroke recurrence?

Xiao Zhang, a pharmacist, suddenly received a call from his cousin, saying that his aunt had a stroke and was hospitalized. The doctor asked her to take clopidogrel and aspirin for "double-antibody" treatment. His cousin asked Xiao Zhang if it was necessary to take two drugs.

The earlier the stroke (commonly known as stroke) is treated, the better, and the treatment window is best within the golden 3 hours. Stroke has the characteristics of high morbidity, high mortality and high disability rate, which not only causes serious adverse consequences to the patient himself, but also brings a heavy burden to the family and society. Therefore, it is very important to do a good job in secondary prevention. Secondary prevention of stroke includes statin lipid regulation, blood pressure control (<130/80mmHg) and antiplatelet treatment strategies. Xiao Zhang's aunt (72 years old) had a mild stroke and did not undergo thrombolytic therapy. She usually had hypertension and diabetes, and did not have atrial fibrillation. Her blood pressure and blood lipids were well controlled during hospitalization. The ABCD2 score of stroke risk prediction assessment in the emergency department was 5 points. In her case, there is a high risk of recurrence in the short term. To balance the risk of ischemia and bleeding, aspirin combined with clopidogrel should be given as soon as possible for 21 days of "dual anti" treatment, and if necessary, 90 days of treatment. After that, aspirin and clopidogrel can be used as first-line medications for long-term secondary prevention.