Know a little about “medicine” | Can I use ibuprofen to relieve pain if I have aspirin-treated asthma?

Aunt Zhao has a history of asthma. She had aspirin asthma last year when she took aspirin. Recently, she wanted to use ibuprofen to relieve the pain of joint pain. But when she went to the hospital to get the medicine, the doctor did not recommend it. Why?

Aspirin asthma is a serious drug-induced disease. It is caused by drugs such as aspirin that inhibit the airway cyclooxygenase pathway, reducing the synthesis of prostaglandin E. As a result, arachidonic acid, the raw material for synthesizing prostaglandin E, produces excessive leukotrienes under the action of lipoxygenase, causing a strong bronchial constriction effect and triggering asthma.

In addition to aspirin, some other non-steroidal drugs such as indomethacin, ibuprofen, diclofenac, flurbiprofen axetil, etc. can also induce aspirin asthma. Therefore, it is not recommended to use the above drugs for pain relief. Celecoxib, acetaminophen, etc. can be used. At the same time, it is necessary to monitor well during the medication process and be alert to the recurrence of asthma.