Eat less and live longer. Are there any rules for fasting?

Recently, Brother Rong seems to be particularly fond of talking about topics related to food.

no way,

Although Rong Ge has lost the qualification to be a foodie,

But if you don't eat well,

Or to be more precise, it doesn't taste good.

You will gain weight, and this is the starting point of all tragedies.

What we are going to do today is say goodbye to eating!

Well, it’s not that decisive. To be exact, it’s fasting.

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This word is still very popular now.

Many health and weight loss institutions

Everyone has their own fasting regimen.

It even has its own set of "theoretical" foundations.

Everything that can be drawn from ancient and modern times, both at home and abroad,

I wish it could encompass half of the history of human civilization.

Click on the video to see what fasting is all about

So is there any scientific basis for this thing?

Of course there must be.

In fact, he has won the Nobel Prize more than once.

It's just not as simple as you think.

Let's first clarify a key concept: autophagy.

The cells are damaged, degenerated,

Aging proteins or organelles,

The process of transport to lysosomes and degradation.

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The lysosome here is an organelle inside the cell.

Contains enzymes for digesting proteins, carbohydrates, and fats.

You know,

The autophagy mechanism controls many physiological functions of the human body.

When the human body is hungry or in other stress reactions,

Cell autophagy can quickly provide energy to the human body.

After the body is infected,

Cell autophagy can destroy viruses and bacteria.

Can eliminate aging, damaged organelles and proteins,

It is of great significance to human anti-aging.

If we compare cells to the cars we drive,

Then the car will wear out, age,

Bumping around and eventually getting scrapped.

Of course we can change cars.

But you can also repair the car and replace parts.

Which method to choose?

That depends on what is more cost-effective.

For example, if your car is soaked in water,

To be on the safe side, it is better to deal with it at a low price.

But if you replace parts and do maintenance, you can keep the car in good condition.

I'm afraid everyone wants to continue driving.

Cell autophagy is an efficient mechanism for replacing parts.

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But how to activate autophagy?

The earliest method verified by everyone

It's about increasing glucagon.

This name looks familiar, right?

It and insulin are brothers, one grows while the other declines.

Regulate our blood sugar levels.

When we eat,

Insulin rises, glucagon falls,

If we fast,

Insulin drops, glucagon rises,

The process of glucagon rising

It stimulates cell autophagy.

This is a major cause of cellular autophagy.

Stop eating.

Depriving the body of the food, energy, and nutrients it needs,

This is what we often call fasting.

It can stimulate cellular autophagy.

At the same time, it activates the cell's self-repair function.

There is also a regulatory enzyme called target of rapamycin,

When it is activated, it inhibits autophagy.

When it is dormant, it may induce autophagy.

Therefore, many manufacturers produce this enzyme.

Trying to regulate cellular autophagy.

However, it is still in an experimental state.

As we age,

The autophagy ability of human cells will gradually decline.

Finally lost.

The consequences of losing the ability to autophagy are very terrible.

If the system does not clean up abnormal proteins and organelles for a long time,

It will lead to the accumulation of a large amount of harmful substances.

Low work efficiency leads to various diseases.

For example, Alzheimer's disease, which causes cognitive impairment,

and cancer,

A large number of studies have found that

Stimulating autophagy can improve Alzheimer's disease.

Cancer can also be suppressed by so-called starvation of cancer cells.

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Of course, this also requires

Only a large amount of new data can prove it.

For the elderly,

If the autophagy mechanism declines,

Autophagy must be stimulated by special means.

Intermittent fasting is a good method.

That is 5+2, 5 days of normal eating and 2 days of fasting,

On the fasting day, you can only take in 500 calories.

And try to finish eating in the shortest possible time.

For example, four hours.

Because once eating is resumed, autophagy stops.

You have to be hungry long enough.

Remember, many studies have found that

All long-lived people eat relatively little.

It is healthier to eat less while ensuring nutrition.

It has been confirmed in animal experiments that eating less can prolong life.

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Source: China Digital Science and Technology Museum

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