How much estradiol is best for egg retrieval

Many people do not know what estradiol is. In fact, it has great clinical manifestations. Whether the estradiol level is slightly low or high, it may reflect the condition of the eggs. Some people who have already done IVF ask, how high does the estradiol level need to be to be able to retrieve eggs for IVF? How much estradiol is best for egg retrieval for IVF?

The standard value of estradiol for women is 48-521pmol/L in the early ovulation period, 70-1835pmol/L in the ovulation period, and 272-793pmol/L in the middle and late ovulation period. Generally, the concentration of estradiol is 300pmol/L per egg. The more eggs there are, the higher the blood volume will be. On the contrary, the fewer eggs there are, the lower the blood volume will be.

Before egg retrieval for in vitro fertilization, the estradiol level is actually not the most important evaluation indicator. Instead, it depends on the number and quality of eggs grown at the same time to determine whether egg retrieval for in vitro fertilization is possible. The reason is that different ovulation induction plans and ovaries result in different numbers of eggs obtained, and therefore different estradiol values. Some people can ovulate more than ten eggs at a time, so the estradiol value will be very high, while some people can only ovulate a few eggs at a time, so the estradiol value will be lower.

So in that case, is there an optimal value for estradiol during egg retrieval for in vitro fertilization? Of course there are, but what I want to talk about is the maximum value of estradiol. Generally speaking, if the estradiol value is higher than 15000pmol/L, it may cause ovarian hyperstimulation syndrome, and if it is higher than 20000pmol/L, there is a higher probability of causing it. Therefore, the estradiol level before IVF egg retrieval should not be higher than 20,000 pmol/L.

I still want to say one more thing. The value of estradiol is not a valid reference standard for in vitro fertilization egg retrieval, and the value of estradiol will be different for different people, so don't use the standard values ​​you see on the Internet as a standard for your own measurement.