Will early stage breast ductal carcinoma metastasize?

Breast ductal carcinoma is a common malignant disease in women. In the early stages of breast ductal carcinoma, it needs to be treated early and a treatment plan should be developed based on the condition. Breast ductal carcinoma may also metastasize in the early stages, so you need to pay more attention to the progression of your disease and maintain a happy mood.

Will early stage breast ductal carcinoma metastasize?

Breast cancer is one of the most common malignant tumors in women, and ductal carcinoma is the most common pathological type of breast cancer, accounting for about 70% of all breast cancer patients. Once breast ductal carcinoma metastasizes and progresses, its prognosis becomes significantly worse, with a median survival time of only 15 to 30 months.

Causes and common diseases:

The etiology and pathological mechanism of breast cancer have not been fully elucidated, but epidemiological surveys have found that early age of menarche, late age of menopause, infertility and age of first full-term birth are all related to the occurrence of breast cancer, indicating that the occurrence of breast cancer is closely related to female endocrine system. The risk of breast cancer among people with a history of breast cancer in their first-degree relatives is three times that of the general population, indicating that genes are also an important factor affecting the occurrence of breast cancer.

Differential diagnosis:

Breast ductal carcinoma Ductal carcinoma is divided into two groups: microinvasive ductal carcinoma and invasive ductal carcinoma. The criteria for invasive ductal carcinoma are:

(1) Cells are atypia, with enlarged and darkly stained nuclei, uneven chromatin distribution, and an increased nuclear-cytoplasmic ratio.

(2) The cell arrangement is extremely disordered, and tumor cells form various arrangements within the ducts.

(3) Cancer cells infiltrate the surrounding stroma, the fibrous stroma around the cancer cells proliferates, and the proliferating fibrous stroma breaks at the contact point with the cancer cells. Actin immunohistochemical staining is negative around the cancer cell nests, or positive around the cancer cell nests and breaks, and cannot surround the cancer cell nests. Minimally invasive ductal carcinoma: meets the first three criteria and also has one or more small, clear microscopic foci of infiltrating fibrous stroma. Proliferative breast lesions include fibroadenosis, fibroadenoma, ductal papillomatosis, and intraductal epithelial hyperplasia.

The patient's nipples will undergo abnormal changes, leading to nipple erosion and itching in the nipple area. Most patients will have severe lumps in the areola or other parts of the breast. At the beginning, the nipple is obviously desquamated, and small cracks appear in the patient's nipple. Nipple desquamation will be accompanied by a small amount of secretion and scabs will form. After removing the scabs, a bright red eroded surface can be seen, and it will not heal for a long time. When the patient's entire nipple is affected, it will often invade the patient's surrounding tissues. As the lesion continues to progress, the nipple will disappear entirely.