How to treat cervical HPV16 positive

When female friends are doing examinations and see the results showing that their cervix is ​​HPV16 positive, they don’t care too much. This actually reflects that their bodies have developed genital warts, but the disease is still in the incubation period and they haven’t felt more obvious clinical manifestations in their bodies. However, they should still seek treatment in time, and the result may not only be due to genital warts, but also cervical cancer.

The results of HPV subtype testing in patients with genital warts found a total of 21 HPV subtypes, among which the incidence of HPV16 subtype was 14.79%, ranking third among the 21 HPV subtypes detected; after HPV subtype testing in patients with genital warts, it was found that there were 20 HPV subtypes, among which the incidence of HPV16 subtype was 17.89%, ranking fourth among the 20 HPV subtypes detected; HPV subtype testing in patients without genital warts found a total of 17 HPV subtypes, among which the incidence of HPV16 subtype was 17.86%, ranking third among the 17 HPV subtypes detected; HPV subtype testing in the skin lesions of patients with genital warts found a total of 21 HPV subtypes, among which the incidence of HPV16 subtype was 14.79%, ranking first among high-risk HPV subtypes. This indicates that HPV-6, 11 and 16 are the main pathogens of HPV infection in patients with condyloma acuminatum.

Cervical cancer

Cervical cancer is the most common malignant tumor of the female reproductive tract, and HPV infection is closely related to the occurrence of cervical cancer. A large amount of epidemiological and molecular biological data show that HPV infection is closely related to the occurrence of cervical cancer, especially high-risk HPV, which is an important pathogenic factor of cervical cancer. Among them, HPV16/18 is the most common type, followed by HPV33.

Previous methods for detecting HPV infection were technically complex, with poor reproducibility of results, and the need to collect specimens again. Patients had poor compliance, making them difficult to be widely used in clinical practice. Therefore, most hospitals failed to routinely test for HPV infection when performing cytology and histology examinations of cervical lesions. Persistent infection with high-risk HPV causes CIN to continue to develop, increasing the relative risk of cervical cancer.

With the help of HPV-DNA gene testing technology, early diagnosis and treatment of HPV virus has become a reality. This method has significantly higher sensitivity in identifying high-grade lesions than previous detection methods, and greatly reduces the false negative rate. Therefore, it can be used for rough screening of high-risk populations. If used properly, this method can even reach a diagnosis rate of 98% for early HPV virus carriers.