50-year-old woman menopause

As women age, their ovaries begin to age, so when they are around 50 years old, they begin to enter menopause due to endocrine and other reasons. Women in menopause may experience symptoms such as bad temper and poor sleep quality. Although we can use some methods to delay the onset of menopause, we cannot avoid it. So, how do 50-year-old women go through menopause?

Perimenopausal syndrome, also known as menopausal syndrome (MPS), refers to a group of syndromes characterized by autonomic nervous system dysfunction and accompanied by neuropsychological symptoms caused by fluctuations or decreases in sex hormones before and after menopause in women. Menopause can be divided into natural menopause and artificial menopause. Natural menopause refers to the exhaustion of ovarian follicles, or the loss of response of the remaining follicles to gonadotropins. The follicles no longer develop and secrete estrogen, and cannot stimulate the growth of the endometrium, leading to menopause. Artificial menopause refers to surgical removal of both ovaries or other methods of stopping ovarian function, such as radiotherapy and chemotherapy. Removal of the hyster alone while retaining one or both ovaries is not considered artificial menopause.

The underlying cause is ovarian failure due to physiological, pathological or surgical reasons. Once the ovarian function fails or is removed and destroyed, the estrogen secretion by the ovaries will decrease. There are more than 400 types of estrogen receptors in the female body, distributed in almost all tissues and organs of the female body. They are controlled and dominated by estrogen. Once the estrogen decreases, it will cause degenerative changes in organs and tissues, resulting in a series of symptoms.

1. Neurotransmitters

Hypothalamic neurotransmitters such as opioid peptides (EOP), epinephrine (NE), and dopamine (DA) are significantly correlated with the occurrence of hot flashes. Serotonin (5-HT) has regulatory functions on endocrine, cardiovascular, emotional and sexual life.

2. Genetic factors

The twin sisters' perimenopausal syndrome started at exactly the same time, and their symptoms and duration were also very similar. Individual personality traits, neurological type, cultural level, occupation, social relationships, family background, etc. are related to the onset and severity of perimenopausal syndrome. This suggests that the occurrence of this disease may be related to higher nervous activity.