If you want to abort the baby just one week into your pregnancy, the best way is to have an artificial abortion or medical abortion in time. Both methods of abortion have certain time limits. The sooner you do it, the faster your condition will improve. After the operation, you should pay more attention to your body care to avoid any bacterial infection. The advantages of medical abortion are that the method is simple, does not require intrauterine operation, and is non-traumatic. Since the 1990s, drugs for medical abortion have become increasingly sophisticated. The more mature and commonly used methods are mifepristone and prostaglandin, with a complete abortion rate of over 90%. Mechanism of action Mifepristone has an anti-progesterone effect. Its affinity for the endometrial progesterone receptor is significantly higher than that of progesterone. Therefore, it can compete with the progesterone receptor in the decidua, block the activity of endogenous progesterone, and interfere with pregnancy. Due to the necrosis of the decidua during pregnancy, endogenous prostaglandins are released, which promote uterine contraction, cervical softening and opening, and the expulsion of the fetal sac. The prostaglandins used in my country are misoprostol and carboprost methyl ester suppositories. There are also gemeprostone and sulfaprostone available abroad. Different regions have slightly different regulations on the gestational age at which medical abortion can be performed. Taking Beijing as an example, women with a gestational age of less than 49 days can have a medical abortion in an outpatient clinic. However, patients with a gestational age of 10-16 weeks have a higher risk of bleeding during forceps curettage, so they have begun to use mifepristone combined with prostaglandins for medical induction of labor, but they need to be hospitalized. Indications 1) Healthy women aged 18-40 years who are diagnosed with normal intrauterine pregnancy (last menstrual period ≤ 49 days) and voluntarily request to use medication to terminate pregnancy; 2) High-risk candidates for artificial abortion, such as those with reproductive organ malformations (except rudimentary uterine horn), severe pelvic deformity, extremely tilted uterus, cervical dysplasia or tough uterus, scarred uterus, multiple artificial abortions, etc. (Note: Even if these patients choose medical abortion, they still have high-risk factors for medical abortion. The failure rate of medical abortion and the chance of post-abortion bleeding are higher than those of patients without high-risk factors); 3) Those who have concerns or fears about surgical abortion. Contraindications 1) Contraindications of mifepristone: endocrine diseases such as adrenal glands, diabetes, thyroid glands, abnormal liver and kidney function, history of skin itching during pregnancy, blood diseases and vascular thrombosis, and tumors related to steroid hormones; 2) Contraindications of prostaglandins: cardiovascular diseases such as mitral stenosis, hypertension, hypotension, glaucoma, gastrointestinal dysfunction, asthma, epilepsy, etc., or those who are allergic to prostaglandins; 3) Those with allergic constitutions and those with severe vomiting during pregnancy; 4) Anemia, hemoglobin of 100g/L or below; 5) Pregnancy with an IUD; 6) Ectopic pregnancy or hydatidiform mole; 7) Smoking more than 10 cigarettes a day or alcohol abuse; 8) Frequent business trips, coming to Beijing from other places, living far from medical institutions and unable to seek medical treatment and follow-up in time; 9) Untreated genital tract inflammation, such as vaginitis, acute suppurative cervicitis or subacute cervicitis, acute or chronic pelvic inflammatory disease, sexually transmitted diseases, etc. Pre-medication treatment 1) The doctor should explain the medication method, efficacy and possible side effects to the recipient, and the recipient can make a voluntary choice; 2) Physical examination and testing are the same as vacuum aspiration; 3) The pros and cons of medical abortion should be explained to pregnant women, and they can make a natural choice. |
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