What to do if the follicle does not break after injection

If a woman wants to have normal reproduction, she must produce qualified eggs. If the eggs are unqualified, infertility will occur. After the egg matures, it will be released from the follicle. The infertility of many women is largely related to the inability of the follicle to produce eggs normally. The best way is to actively puncture the follicle to release the egg, but this method does not work for some people. So, what should we do if the follicles do not break even after the injection?

Unruptured follicle syndrome, also known as luteinized follicle or luteinized unruptured follicle syndrome. It refers to the failure of mature ovarian follicles to rupture due to various reasons, making it impossible for the eggs to be discharged. Without eggs, conception is of course impossible.

A normal follicle will form a corpus luteum and secrete estrogen and progesterone only after ovulation. However, in patients with unruptured follicle syndrome, the egg becomes luteinized and secretes estrogen and progesterone before it is released. Therefore, general examination methods often cannot confirm the absence of ovulation, but may mistakenly believe that ovulation has occurred. This has also resulted in many patients with unruptured follicle syndrome not being diagnosed in a timely manner.

What to do if the follicle does not rupture

To treat the disease of unruptured ovarian follicles, first of all, its diagnosis must exclude various factors causing infertility, directly observe under laparoscopy or take peritoneal fluid to measure hormone levels, or use B-type ultrasound to observe follicular development and ovulation. At the same time, its treatment is also relatively difficult. Currently, the method of inducing ovulation with human menopausal gonadotropin and chorionic gonadotropin has achieved certain therapeutic effects. Moreover, since this disease is also related to mental factors, the patient's mental treatment cannot be ignored. The current common treatment methods mainly include the following aspects:

1. Use B-ultrasound to monitor ovulation. After taking ovulation-inducing drugs or during the natural cycle, it is best to use B-ultrasound to detect ovulation. At the same time, ultrasound monitoring can also clearly observe the thickness and morphology of the endometrium, which has a certain role in predicting pregnancy.

2. Ovulation induction treatment. There are many types of ovulation-inducing drugs, which produce their effects through different mechanisms. These drugs should be used with caution and under the guidance of an endocrinologist. If used improperly, not only will they fail to achieve the therapeutic effect, they may sometimes lead to multiple pregnancies, miscarriages, and even ovarian hyperstimulation syndrome.