What are the causes of vulvar leukoplakia?

Vulvar leukoplakia is a disease that has a particularly serious impact on women. This disease will not only affect women's normal life, but also cause a particularly serious psychological burden on women. The main reason is that such a disease is not easy to treat. Therefore, after getting the disease, it is important for us to know the cause of our disease. After finding out the cause, symptomatic treatment is relatively easy. Let's take a look at the causes of vulvar leukoplakia.

Etiology and pathogenesis

1. Vulvar infection and inflammatory stimulation: This is the main cause of vulvar leukoplakia, accounting for about 50% of patients. There are many factors that cause vulvar infection and inflammatory stimulation, such as poor hygiene habits, wearing synthetic underwear, unclean sanitary products, bathing in a bathhouse, swimming in a bathhouse, etc., which lead to vaginal inflammation. If not treated in time, the inflammatory secretions will infiltrate the perineum, and long-term infection and stimulation will damage the skin and mucous membranes, causing redness, swelling, ulcers and degeneration, which will gradually develop into vulvar leukoplakia.

2. Endocrine disorders: Endocrine diseases are caused by pathological changes in the endocrine glands and tissues themselves, or by endocrine disorders due to genetics, enzyme defects, immune function and other reasons. Through the determination of tritium (H3) labeled thymidine, it is believed that there is a protein hormone in the dermis that can inhibit the division and growth of epidermal cells and only acts locally on the epidermis with tissue specificity, called inhibin. It causes an imbalance between local connective tissue hyperplasia and the stimulation of epidermal metabolism at that location, leading to vulvar leukoplakia.

3. Genetic factors: About 10-30% of patients with vulvar leukoplakia. It is caused by genetics. The genetically caused vulvar leukoplakia is mainly atrophic type, and the patients are mainly young girls. In clinical practice, the first thing to pay attention to for patients under 15 years old is genetic factors, and inquire whether there are patients with vulvar leukoplakia in their parents' family.

4. Other diseases: such as diabetes, vitiligo, vulvar eczema, vulvar itching, etc., if the drugs are abused or the treatment is improper, it may also cause or aggravate the formation and development of vitiligo.

Through the above introduction, we know the cause of vulvar leukoplakia in women. After having such a disease, we must take good care of ourselves while undergoing treatment, adjust our emotions, and pay attention to a light diet. In particular, we must wear breathable, all-cotton underwear, keep the female vulva clean, and avoid scratching it.