What are the manifestations of secretory endometrium?

The so-called female secretory period is actually the period from the time the egg is mature and discharged to the time when menstruation arrives, which is generally about 14 days. During the secretory period, the woman's endometrium is also constantly changing. Many women are not very clear about this and will not learn about this in detail until the pregnancy preparation stage. In fact, the thickness of the endometrium will directly affect conception. So what are the manifestations of the endometrium during the secretory period?

From the first day after ovulation, the menstrual period enters the secretory phase. The secretory phase in a normal cycle lasts about 14± days. If the error exceeds 2 days, functional disorder should be considered. Since the endometrium behaves differently every day under the influence of progesterone, it can be precisely timed.

Day 1 of ovulation: Scattered small vacuoles may appear in some glandular epithelial cells on the basis of the late proliferative phase.

Day 2 of ovulation: Many basal vacuoles appear in the glandular epithelium, but at least 50% of the glandular epithelium in the endometrium must have basal vacuoles to be considered the second day of ovulation, which is the 16th day of the menstrual period.

Day 3 after ovulation: The vacuole grows and pushes all the nuclei to the top of the cell, forming a neat circle around the lumen.

Day 4 after ovulation: Some nuclei return to the base, while the glycogen on both sides of these nuclei move toward the lumen.

Day 5 after ovulation: Most of the nuclei have returned to the bottom of the cell. The nuclei are round and vesicular, lightly stained or transparent, the nucleoli are significantly enlarged, and the interstitium is slightly edematous.

Day 6 after ovulation: The gland cavity begins to expand and the gland cells become short. The top edge is fragmented due to apical secretion.

Day 7 after ovulation: Glycogen is found in the glandular cavity, the glandular cells are cubic, and interstitial edema is obvious.

Day 8 after ovulation: Interstitial edema reaches its peak.

Day 9 after ovulation: Interstitial edema begins to subside, and the spiral arteries gradually become more obvious, longer, thicker, and spirally twisted. Interstitial cells are round.

Day 10 after ovulation: The interstitial cells around the arteries become predecidual cells, forming a broad and thick predecidual cell coat with large, round and transparent nuclei. The glandular epithelium is significantly serrated, and there are residual secretions in the glandular cavity.

Day 11 after ovulation: The interstitial cells of the dense layer close to the surface epithelium differentiate into pre-decidual cells known as granulosa cells.

Day 12 after ovulation: The interstitial cells of the entire dense layer are fully differentiated.

Day 13 after ovulation: The endometrium shrinks, the glands collapse into a serrated shape, and the anterior decidual stroma becomes extremely dense.

Ovulation day 14: Obvious bleeding and necrosis occur.

The above is an introduction to the manifestations of the endometrium in the secretory phase. In fact, for women, even if they do not have much understanding of the changes in the endometrium, it will not affect pregnancy, unless the endometrium is really too thin or too thick. In this case, treatment is needed before pregnancy.