Causes of corpus luteum deficiency in women

I believe that everyone is still not familiar with what the corpus luteum is. The corpus luteum of female friends plays the function of secreting progesterone. If there is a problem with the corpus luteum, it will be very harmful to female friends. Corpus luteum deficiency can easily lead to symptoms of miscarriage in female friends. We must find out the cause of corpus luteum deficiency in time, and then we must make targeted treatment based on the cause of corpus luteum deficiency. Below we will introduce to you the causes of female corpus luteum deficiency.

The corpus luteum is a vascularized gland-like structure that is rapidly transformed from the ovarian follicle after ovulation.

After ovulation, the remaining follicular wall collapses, and the connective tissue and capillaries of the follicular membrane extend into the granulosa layer. Under the action of LH, it evolves into a larger cell cluster rich in capillaries and with endocrine function. It appears yellow when fresh and is called corpus luteum.

What is the cause of corpus luteum insufficiency? Many women have habitual miscarriage, which is extremely harmful to women. Corpus luteum insufficiency is a very common cause of habitual miscarriage. The maintenance of normal corpus luteum function depends on the improvement of the function of the hypothalamus-pituitary-ovarian gonadal axis in women. Abnormalities in the follicular phase as well as the luteal phase of women may also lead to luteal dysfunction.

reason

1. Women have insufficient FSH secretion during the follicular phase, and the FSH and estradiol levels in the follicular fluid are low.

2 Experts say that insufficient LH peak during ovulation is also a cause of corpus luteum deficiency in women.

3. Women’s luteal phase LH secretion is insufficient or its pulsed secretion is insufficient.

4. The steroid hormone receptors in women's endometrial cells are abnormal and their responsiveness to the hormones secreted by the corpus luteum is relatively low. Even if the corpus luteum function is normal, endometrial development will be poor.

In the above article, we introduced what the corpus luteum is. We know that the corpus luteum plays a very important role for female friends. If the corpus luteum is insufficient, it can easily lead to miscarriage in pregnant women. Therefore, we must pay attention to this symptom. The above article introduces in detail the reasons for the deficiency of the corpus luteum in women.