What are the dangers of taking too much ibuprofen sustained-release capsules? What should I do if I have stomach pain and vomiting after taking ibuprofen?

Ibuprofen capsules are a common painkiller that is effective for muscle pain, nerve pain, migraine, toothache, dysmenorrhea, etc. It can also be used to treat fever caused by colds. Children over 6 months old can also take it. However, you can't take too much ibuprofen. What are the dangers?

What are the dangers of taking too much ibuprofen sustained-release capsules?

Ibuprofen should not be used for a long time or in large quantities. It can be used to relieve pain for no more than 5 days and to relieve fever for no more than 3 days. If the symptoms are not relieved, you need to see a doctor.

Ibuprofen can inhibit the synthesis of prostaglandins and has strong anti-inflammatory, antipyretic and analgesic effects. It can also be used to treat fever, rheumatic and rheumatoid arthritis and chronic dull pain.

However, long-term use may lead to the following adverse reactions:

Digestive tract damage: including heartburn or indigestion, gastrointestinal ulcers and bleeding, etc.

Renal damage: Long-term use is often accompanied by increased serum urea levels and edema, which can lead to nephrotic syndrome, renal papillary necrosis or renal failure.

Liver damage: elevated transaminases

What to do if you have stomach pain and vomiting after taking ibuprofen

As mentioned above, although ibuprofen has a good effect in relieving various pains, its worst side effect is the damage to the gastric mucosa. In addition to ibuprofen, other non-steroidal drugs can also damage the gastric mucosa, including (indomethacin, nimesulide, indomethacin, diclofenac sodium, etc.).

The reason why these drugs can damage the gastric mucosa is mainly because they can affect the repair function of the gastric mucosa, causing the gastric mucosa to become weak, making it more susceptible to invasion and damage by some damaging factors.

Therefore, do not take ibuprofen for a long time or in large quantities, and do not use ibuprofen or other analgesics just for random pain. Especially for patients who already have stomach diseases, analgesics should be used more strictly.

Since symptoms of stomach pain and vomiting have appeared, the first thing to do is to stop taking ibuprofen, go to the hospital to seek alternative medications, pay attention to the dosage of the medication, and pay attention to the maintenance of your stomach.

If you must take it, you can add a gastric mucosal protective agent to protect the gastric mucosa and reduce the damage of ibuprofen to the gastric mucosa. Currently, the commonly used gastric mucosal protective drugs mainly include pectin bismuth, aluminum carbonate magnesium, sucralfate, potassium bismuth citrate, etc., which can effectively form a protective film on the gastric mucosa. It is recommended to take gastric mucosal protective drugs half an hour before taking ibuprofen.

Does ibuprofen sustained-release capsules reduce fever?

Can relieve fever symptoms.

Ibuprofen relieves fever and pain by inhibiting the activity of the key enzyme (cyclooxygenase) that synthesizes prostaglandins and reducing the production of prostaglandins.

In an inflammatory response, a variety of cytokines promote the production of prostaglandins in the hypothalamus, which are pyrogen. They raise the hypothalamic temperature set point, increase heat production, and raise body temperature. Ibuprofen inhibits the production of prostaglandins and stimulates the body to produce "cooling sources", such as vasopressin in the posterior pituitary, to achieve a fever-reducing effect.

(Editor's note: Please follow the doctor's instructions when taking medication, and do not buy and use it blindly.)