When is the best time for women to check their hormone levels?

The six-item hormone test (six-item sex hormone test and six-item reproductive hormone test) is a basic routine urinary system examination for women. China does not have a complete and unified gynecological endocrine estrogen measurement value. In addition, due to the various sources of experimental reagents, measurement methods, data calculations, and different companies used, even if the same hormone sample is collected, the results obtained by each laboratory are not exactly the same.

The six-item sex hormone test has many tests and can detect many symptoms. Therefore, as a common examination item, the six-item sex hormone test is a common examination method for patients with endocrine imbalance. Through the six-item sex hormone test, it can be determined whether there is an endocrine disease, and then the treatment method can be determined according to the test results.

Six items of sex hormone test

1. Testosterone (T): 50% of the testosterone in women's body is converted from jugular vein androstenedione, about 25% is metabolized by the adrenal glands, and only 25% comes from the uterus and ovaries. The key function is to promote the growth and development of the clitoris, vulva and mons pubis. It has an inhibitory effect on estrogen and has a certain impact on systemic metabolism. The normal concentration of T in women's blood is 0.7-3.1nmol/L. High blood T is called hypertestosteroneuria, which can cause infertility. When suffering from polycystic ovary syndrome, blood T value also increases. Based on clinical symptoms, other growth hormones can be measured if necessary.

2. Estradiol (E2): It is secreted by the eggs in the uterus and ovaries. Its key function is to promote the transformation of the uterine wall into the reproductive stage and to promote the growth and development of women's secondary sexual characteristics. The concentration of blood E2 is 48-521 picomoles/L in the early ovulation period, 70-1835 picomoles/L in the ovulation period, and 272-793 picomoles/L in the middle and late ovulation period. Low values ​​are common in low ovary function, premature ovarian failure, and Sheehan's syndrome.

3. Progesterone value (P): It is metabolized by the luteinizing hormone of the uterus and ovaries. Its key function is to promote the change of the uterine wall from the reproductive period to the metabolic period. The blood P concentration should be 0-4.8 nmol/L before ovulation and 7.6-97.6 nmol/L in the middle and late ovulation period. Low blood P values ​​are easily consumed in the middle and late ovulation period, which is common in luteal insufficiency, abnormal uterine bleeding caused by ovulation-type imbalance, etc.

4. Luteinizing hormone (LH): A glycoprotein growth hormone metabolized by the alkaline somatic cells of the anterior pituitary gland. It mainly promotes the ovulation period. Under the synergistic effect of FSH, it produces progesterone and metabolizes estrogen. The concentration of blood LH is 2-15mIU/ml in the early ovulation period, 30-100mIU/ml in the ovulation period, and 4-1b250IU/ml in the middle and late ovulation period. The standard value during the non-ovulation period is generally 5 to 25 mIU/ml. Less than 5mIU/ml indicates insufficient gonadotropin effect, which is common in Sheehan syndrome. If high FSH and LH are increased, ovarian failure is very certain and no further tests are needed. LH/FSH ≥ 3 is one of the bases for diagnosing polycystic ovary syndrome.

5. Prolactin (PRL): It is secreted by trophoblasts, one of the eosinophilic cells in the anterior pituitary gland. It is a simple protein growth hormone. Its main function is to promote mammary gland proliferation, milk conversion and milk discharge. During the non-breastfeeding period, the standard value of blood PRL is 0.08～0.92nmol/L. Higher than 1.0nmol/L is hyperprolactinuria. Excessive prolactin can inhibit the metabolism of FSH and LH, suppress the ovaries, and suppress the ovulation period.

6. Promote the conversion of oocytes into growth hormone (FSH): a glycoprotein growth hormone metabolized by the alkaline somatic cells of the anterior pituitary gland. Its key function is to promote the development and improvement of the uterus and ovaries. The concentration of blood FSH is 1.5~1b250IU/ml in the early ovulation period, 8~2b250IU/ml in the ovulation period, and 2~1b250IU/ml in the middle and late ovulation period. Generally, 5 to 4b250IU/ml is used as the standard value. Low FSH values ​​are common during estrogen-progestin treatment, Sheehan's syndrome, etc. High FSH is common in premature ovarian failure, uterine and ovarian insensitivity syndrome, primary amenorrhea, etc.