Letrozole tablets are a new generation of aromatase inhibitors, which are synthetic benzyltriazole compounds. Letrozole tablets inhibit aromatase, reduce estrogen levels, and thus eliminate the stimulating effect of estrogen on tumor growth. They are particularly suitable for postmenopausal breast cancer patients. So, how does Letrozole work? First, surgical studies have shown that Furui (letrozole tablets) can effectively inhibit the conversion of androgen to estrogen. The estrogen of postmenopausal women mainly comes from the aromatization of androgen precursors in the venous tissue, so it is particularly suitable for postmenopausal breast cancer patients. Secondly, Furui (letrozole tablets) as a new generation of aromatase inhibitor, its body specificity is 150 to 250 times stronger than the first generation aromatase inhibitor aminoglutethimide. Because of its high selectivity, it does not affect hormone drugs, mineralocorticoids and thyroxine. Large doses have no inhibitory effect on the metabolism of renal corticosteroid compounds, and therefore has a high therapeutic index. Finally, various preclinical studies have shown that Furui (letrozole tablets) has no potential toxic side effects on systemic systems and target organs, and has the characteristics of good tolerance and strong medicinal value. Based on a comprehensive review of many large-scale clinical studies at present, it is confirmed that Furui (letrozole tablets) has extraordinary clinical efficacy in all stages of the treatment of postmenopausal breast cancer, namely in the first-line treatment of advanced breast cancer, neoadjuvant treatment of primary breast cancer, and subsequent enhanced treatment of early breast cancer, with fewer side effects and high patient compliance. |
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