Standards for hcg values ​​after transplantation

In vitro fertilization has also become an increasingly mature procedure in clinical medicine. It can effectively solve problems such as women's difficulty in becoming pregnant. However, IVF transplantation is also a relatively complicated process because it takes a long time, and after the transplantation, women also need to pay close attention to whether there are any changes in their bodies. So what is the standard of hcg value after the transplantation?

1. What is the normal hCG level on the 14th day of IVF?

What is the normal hCG value on the 14th day of test tube transplantation? It depends on whether fertilization is successful. The specific value is related to individual differences. When the transplantation is successful, HCG will exceed 5IU/L.

During pregnancy, the normal value of blood hCG is <10μg/L, and the normal value of β-hCG is <3.1μg/L. β-hCG is a part of hCG. Generally, the β-hCG radioimmunoassay value of a normal woman is less than 3.1. If it exceeds 5, the possibility of pregnancy can be considered. If it exceeds 10, pregnancy can be basically confirmed.

It should be noted that some hospitals use ng/ml (nanogram/milliliter) as the unit on their test reports. This is an old unit, 1ng/ml=1μg/L.

What is hCG?

hCG, also known as human chorionic gonadotropin, is a glycoprotein secreted by the trophoblast cells of the placenta. It is composed of α and β dimers of glycoprotein. Human chorionic gonadotropin (HCG) αβ, synthesized by syncytial trophoblasts. A glycoprotein hormone with a molecular weight of 36,700. The α subunit is basically similar to FSH (follicle stimulating hormone), LH (luteinizing hormone) and TSH (thyroid stimulating hormone) secreted by the pituitary gland, so they can cross-react with each other, while the structures of the β subunits are different. β-HCG is similar in structure to β-LH, but the last 24 amino acids are not present in β-LH.

hCG has the following functions:

(1) It has the functions of FSH and LH, maintaining the life of the menstrual corpus luteum and making it enlarge into the corpus luteum of pregnancy;

(2) Promote the aromatization of androgens into estrogens and stimulate the formation of progesterone;

(3) Inhibit the stimulation of lymphocytes by plant lectins. Human chorionic gonadotropin can be adsorbed on the surface of trophoblast cells to prevent embryonic trophoblast cells from being attacked by maternal lymphocytes.

(4) LH-like function: before the fetal pituitary gland secretes LH, it stimulates the fetal testicles to secrete testosterone to promote male sexual differentiation; it can also promote gonadal development, and in men, it can stimulate the activity of interstitial cells in the testicles and increase the secretion of androgen (testosterone). It is of great significance for the treatment of male patients with combined pituitary deficiency. It can not only promote gonadal development and the secretion of male hormones, but also promote the development of secondary sexual characteristics.

(5) Can bind to the TSH receptors of maternal thyroid cells and stimulate thyroid activity.