HCG rises after hydatidiform mole descends

Women with hydatidiform mole may experience vaginal bleeding and acute abdominal pain. Hydatidiform mole must be examined and treated in time, otherwise it is easy to seriously endanger the life and health of the pregnant woman. Normally, hCG will recover after treatment, and regular follow-up is required to observe changes in hCG. So, what should you do if hCG in hydatidiform mole is elevated? The following editor will give you a detailed introduction.

What to do if hcg level in hydatidiform mole is elevated

The blood hcg level of hydatidiform mole is usually reduced after drug treatment. So, what should we do if the hCG level of hydatidiform mole is elevated? Under normal circumstances, after the hydatidiform mole is expelled, the blood cell hCG will decrease steadily. The average time for the first decrease to normal is 9 weeks, and no more than 14 weeks. If hCG continues to be abnormal after the hydatidiform mole is expelled, gestational trophoblastic tumor should be considered. High-risk hydatidiform mole should be considered when the following high-risk factors are present: hCG>100,000U/L; the uterus is significantly longer than the corresponding gestational age; the diameter of the uterine and ovarian sphingomyelinating cyst is>6 cm or unilateral sphingomyelinating cyst; age 40 years old; small hydatidiform mole; history of recurrent hydatidiform mole; indications for cesarean section: hyperemesis gravidarum, relatively hyperactive thyroid hormone, etc.

There is a 10% to 20% chance that the condition will worsen, so patients with hydatidiform mole should be followed up regularly. In particular, following up on the changes in HCG in urine or blood can detect the deterioration trend in the early stage, which is very important for the prognosis of the disease. After hydatidiform mole curettage, urine should be checked once a week until the urine pregnancy test is negative, then once a month, and once every three months after half a year, with at least 2 years of follow-up. After follow-up, the patient can become pregnant again.

To prevent the recurrence of hydatidiform mole, great attention should be paid to follow-up after treatment. After evacuation of hydatidiform mole, hCG should be measured once a week until it is negative for 3 consecutive times, and then once a month for at least half a year. From then on, follow-up can be done once every six months for a total of 2 years. Follow-up should pay attention to changes in hematuria and HCG. In addition, a gynecological examination should be performed to understand the state of uterine repair and pay attention to whether the patient has abnormal vaginal bleeding, hemoptysis, and other migratory symptoms. Pelvic ultrasound, chest X-ray or CT examination are performed in parallel.

How does a hydatidiform mole occur?

Hydatidiform mole is also called a small vesicular mole. Hydatidiform mole is caused by the proliferation of villous trophoblasts and interstitial edema after pregnancy, which results in the formation of small blisters of varying sizes. The small blisters are connected by pedicles to form a cluster, and are shaped like red grapes, hence the name. The exact cause of hydatidiform mole is still unclear. It is generally believed to be related to factors such as hypofunction (especially folic acid deficiency), infection (especially viral infection), genetic inheritance and immune dysfunction.