What are the stages of endometrial cancer?

Endometrial cancer is a relatively common and frequent gynecological cancer. The onset of this disease has obvious age characteristics. It is generally more common in middle-aged and elderly women. If you want to detect and treat the disease early, we recommend that you have a gynecological examination every two years starting at the age of 35, and women over 40 should have a gynecological examination once a year. The earlier cancer is discovered, the better the cure. Let’s take a look at the different stages of endometrial cancer.

How is uterine cancer graded?

Internationally, medical researchers classify uterine cancer into four grades. Grade 1, well-differentiated carcinoma, usually refers to a tumor that is confined to the endometrium, occasionally with stratified papillary epithelium, irregular arrangement, and reduced stroma. The second level is moderate involutional cancer. The outline of the uterine gland is not very clear, and part of it will appear as a cancerous mass. The cell poles disappear, and nuclear division is common. The third level is poorly differentiated cancer, in which the structure of the carcinoma line disappears and the whole is in the shape of a cancer mass. Piles of cancer cells erode the interstitium and penetrate into the muscle layer. The fourth grade is markedly undifferentiated cancer, in which the cancer cells are in an immature state, neither differentiated but with obvious mitosis.

There is another type of staging method for cervical cancer, which is roughly divided into two types: localized and diffuse. Localized adenocarcinoma refers to most male cancers. The tumor begins as a sessile or pedunculated tumor in the fundus and cornu uteri. It is very soft and fragile, and bleeding, necrosis, ulceration or infection may occur on the surface. Although this type of disease is very small, it spreads very quickly.

Another type of diffuse adenocarcinoma refers to a tumor that spreads along the endometrial layer, invading the endometrium in large quantities, often appearing in an irregular polyp-like shape. It infiltrates the muscle layer more slowly, the uterus is larger, and symptoms appear earlier. The lesion may spread downward from the uterus and invade the cervical canal.