Does high prolactin affect ovulation?

High prolactin can lead to anovulation, which is also one of the typical symptoms and affects women's pregnancy. However, there are already many treatments now, especially Western medicine treatment targeting the cause of the disease. Surgery and radiotherapy can also be used, and the prognosis is good.

1. Does high prolactin affect ovulation?

Hyperprolactinemia refers to a syndrome caused by internal and external environmental factors, characterized by amenorrhea, galactorrhea, anovulation and infertility. In the past 20 years, great progress has been made in the physiological and biochemical research on PRL, and with the advancement of PRL radioimmunoassay, brain CT and MRI diagnostic techniques, its incidence has also tended to increase. At the same time, the advent of the anti-prolactin drug bromocriptine and the development of transsphenoidal microsurgery have brought new developments in the diagnosis and treatment of HPRL.

2. Treatment Methods

1. Treatment of the cause and primary disease

For example, eliminate adverse mental stimulation, stop taking HPRL-inducing drugs, and actively treat primary diseases such as pituitary tumors, hypothyroidism, Cushing's disease, etc.

2. Surgical treatment

It is suitable for patients with giant adenomas that present compression symptoms, as well as patients with drug-resistant tumors, patients who are unresponsive to bromocriptine treatment, and patients with septicomas that secrete multiple pituitary hormones.

Current transsphenoidal microsurgery

microsurgery), safe, convenient, and easy to perform, with efficacy similar to bromocriptine therapy. Using bromocriptine before and after surgery can improve the efficacy. The disadvantages of surgery are: if the pituitary tumor has no obvious capsule and unclear boundaries, the surgery is difficult to be thorough or may cause damage, resulting in cerebrospinal fluid nasal fistula and secondary pituitary dysfunction.

3. Radiation therapy

It is suitable for non-functional tumors of the HP system and those who are not responsive to drug and surgical treatments. Irradiation methods include: deep X-rays, 60Co, alpha particles and proton rays. Isotope 90 yttrium, 198 gold pituitary implants, etc.

4. TCM treatment of hyperprolactinemia

Traditional Chinese medicine believes that the cause and pathogenesis of this disease is relatively complex, but in principle it can be divided into two categories: deficiency and excess. Deficiency refers to liver and kidney deficiency, insufficient essence and blood, and an empty blood sea. When there is no blood to flow, amenorrhea will occur; when qi and blood are weak and kidney qi is not solid, milk will overflow. Reality

It is caused by liver depression and qi stagnation, blood stasis and phlegm obstruction, which block the meridians and force menstrual blood to flow downward; or it is caused by heat accumulation in the liver meridians and abnormal blood secretion, which forces milk to overflow. Due to insufficient endowment, kidney qi is not strong, essence is not full, liver blood is insufficient, Chong and Ren meridians are not nourished, and there is no way to

It turns into menstrual blood; or due to sexual overwork or long-term illness, the kidney essence is depleted, the liver blood is also deficient, the essence and blood are scarce, the source is cut off, the Chong and Ren meridians are deficient, and the uterus has no blood to discharge, resulting in amenorrhea.