Is FSH 115 normal?

When the follicle-stimulating hormone level shows 115 during the examination, many female friends will be nervous, thinking that this situation is caused by a disease. In fact, this index may change with the changes in one's menstrual cycle and is not fixed. Therefore, a single examination result cannot explain the real problem. You should still do regular follow-up examinations to know whether there is a disease.

Follicle-stimulating hormone is a hormone secreted by the alkaliphilic cells of the anterior pituitary gland. It is composed of glycoprotein and its main function is to promote the maturation of follicles. Follicle-stimulating hormone can promote the proliferation and differentiation of granulosa cells in the follicle and promote the growth of the entire ovary. Its action on the seminiferous tubules of the testicles can promote sperm formation.

Follicle-stimulating hormone is secreted in the human body in a pulsatile manner, and in women it changes with the menstrual cycle. The determination of serum follicle-stimulating hormone is of great significance for understanding the endocrine function of the pituitary, indirectly understanding the functional status of the hypothalamus and ovaries, predicting ovulation time, and diagnosing and treating infertility and endocrine diseases.

Decreased follicle-stimulating hormone is seen in estrogen and progesterone treatment, secondary sexual dysfunction, hypopituitarism, Sheehan syndrome, polycystic ovary syndrome, and advanced adenohypophysitis.

Elevated follicle-stimulating hormone is seen in testicular seminoma, Klinefelter's syndrome, Turner syndrome, primary amenorrhea, congenital ovarian dysgenesis, after treatment with adrenocortical hormones, primary reproductive insufficiency, ovarian obesity, early hyperpituitarism, giant cell degenerative lung cancer, etc.

Taking birth control pills, estrogen, or during pregnancy may affect the determination of serum follicle-stimulating hormone, so care should be taken during testing. And because the physiological changes of follicle-stimulating hormone in serum are large, when judging and interpreting a certain pathological phenomenon, the measurement should be repeated many times to avoid misjudgment.

Gonadotropins (Gn) are glycoprotein hormones that regulate the development of vertebrate gonads and promote the production and secretion of sex hormones. For example, the luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secreted by the anterior pituitary gland work synergistically to stimulate the development of germ cells in the ovaries or testicles and the production and secretion of sex hormones; the human chorionic gonadotropin (HCG) secreted by the human placenta can promote the secretion of progesterone by the corpus luteum of pregnancy. HCG can appear in the urine in the early stages of pregnancy and reaches its peak at two months of pregnancy. It is often used as an indicator of pregnancy in clinical practice.