Precautions for magnesium sulfate pregnancy protection

Pregnant women who have had a history of spontaneous abortion must pay attention to preserving the fetus to avoid another miscarriage. During the process of preserving the fetus, certain preserving drugs may be needed for treatment. For example, magnesium sulfate is a drug that inhibits uterine contractions and can prevent miscarriage. During the medication process, you must follow the doctor's advice. If you have renal insufficiency, you must use it with caution.

Magnesium sulfate is a drug that inhibits uterine contractions. It can prevent miscarriage or premature birth. It has no effect on the fetus. If your uterine contractions are frequent, for the safety of the fetus, it is recommended that you take magnesium sulfate, which has the effect of preserving the fetus. Before and during each medication, regularly observe the pregnant woman's breathing rate, urine output, Mg2+ concentration, heart rate, knee reflex, etc. If the knee tendon reflex is significantly weakened or disappears, or the respiratory rate is less than 16 times per minute, the urine volume is less than 25 ml per hour or less than 600 ml in 24 hours, the medication should be stopped immediately. When using magnesium sulfate, 10 ml of 10% calcium gluconate should be prepared for detoxification.

Renal function must be checked before using magnesium sulfate injection. If renal function is impaired, it should be used with caution and the dosage should be reduced. It should be used with caution or not at all in cases of myocardial damage or heart block. Before and during each medication, check the knee tendon reflex regularly, measure the respiratory rate, observe the urine output, and draw blood to check the blood magnesium concentration. If the knee tendon reflex is significantly weakened or disappears, or the respiratory rate is less than 14 to 16 times per minute, the urine volume is less than 25 to 30 ml per hour, or less than 600 ml in 24 hours, the medication should be stopped immediately.

If chest tightness, chest pain, or shortness of breath suddenly occurs during medication, timely auscultation should be performed and a chest X-ray should be taken if necessary to detect pulmonary edema early. If acute magnesium poisoning occurs, calcium can be used for rescue via intravenous injection. The commonly used one is 10% calcium gluconate injection 10ml slowly injected. During pregnancy preservation treatment, it is not advisable to use it simultaneously with adrenergic b receptor agonists, such as ritodrine, otherwise it is easy to cause adverse cardiovascular reactions. The initial dose for the treatment of moderate to severe pregnancy-induced hypertension, preeclampsia and eclampsia is 2.5-4 g, diluted with 20 ml of 25% glucose injection, and slowly injected intravenously within 5 minutes, followed by intravenous drip of 1-2 g per hour to maintain. The total amount in 24 hours is 30g, which is monitored based on knee tendon reflex, respiratory rate and urine output.

After understanding these contents, we know what are the relevant precautions for magnesium sulfate to preserve the fetus. Pregnant women should be used with caution, and pregnant women should also pay attention to rest during the process of preserving the fetus.