Human papillomavirus cervix in women

The uterus is the place where life is conceived and it is also the channel that maintains the normal physiological function of women. Women have menstruation once a month. Unless there are pathological factors, menstruation is regular and generally does not exceed 28 days. Occasional delays within no more than one week are normal. When a woman's cervix is ​​infected with human papillomavirus, it will cause cervicitis. How should the disease be treated after it occurs?

Medication

1. Local drug treatment Since most warts will resolve on their own within one or two years after infection, for many patients, even with deep destructive treatment methods, one-third of the warts will recur. Therefore, the efficacy of various local treatments for warts should be evaluated with particular caution, and some treatments that can cause permanent scars should not be used. Commonly used ones are:

(1) Cytotoxic agents:

① Fluorouracil (5-FU): 5% 5-FU ointment or 5-FU injection can be used externally, applied to the surface of warts twice a day, with good therapeutic effect. Possible side effects include local pain, chapped skin, edema, allergic reaction, tearing, pigmentation and suppuration.

② Intralesional injection of bleomycin: Some people use 0.05%-0.1% bleomycin (bleomycin) saline solution or 2% procaine solution for local intralesional injection to treat single or several common warts or plantar warts. Depending on the size of the wart, 0.2-0.5 ml is injected each time, once a week. Usually after 2-3 times, the warts will fall off with few side effects.

③0.1%~0.3% retinoic acid ethanol solution: For topical use, once or twice a day, for the treatment of flat warts and common warts, with cure rates of 83% and 39% respectively. Side effects include local mild burning sensation, redness, swelling, desquamation and pigmentation.

(2) Other topical medications: 20% iodine glycoside solution for periungual warts; dinitrochlorobenzene for contact dermatitis induced at the site of refractory warts; 3% formaldehyde solution for local wet compress or soaking, once a day, 15 minutes each time, for 4 to 8 weeks for the treatment of plantar warts; 25% psoralea corylifolia tincture and 30% drynaria tincture for external application for the treatment of flat warts, etc., all have certain therapeutic effects.

2. Systemic treatment

There are many systemic treatments available, but their effectiveness is uncertain.

(1) Antiviral and immunomodulatory treatment: Treatment with drugs such as interferon α, acyclovir, and levamisole. These drugs have antiviral, antiproliferative, and immunomodulatory effects and are considered to have better therapeutic effects. It is especially suitable for patients with intracavitary warts or subclinical infections.

(2) Magnesium oxide treatment: 0.5 g/time, 3 times/day, or methenamine 0.3-0.5 g/time, 3 times/day, is considered to be more effective for flat warts.